Persistant sexual arousal syndrome
Sun, 01/31/2010 - 21:27 | 
Anonymous
I believe I might have this.
Can you please tell me how one can gradually rejuvenate their neuro-endocrine function and boost your prostaglandin E-1/E-3 and Nitric Oxide production?
Is this done my simply not masterbating a for period of time?
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Reply
If you fully discharged your brain's nervous modulation on the release of excessive prostaglandin E2, DHEA, testosterone, and DHT (for PSAS), and dopamine-norepinephrine-epinephrine conversion it may be difficult to get the things on track.
I would like to try.
I would like to try.
Reply
1. Discontinue any sexual activities.
2. Take massages to increase the proper blood circulation.
3. Balance your diet
4. Restore your nervous modulation on your inflammatory hormones release, by taking the proper supplements: Male-Multi-GV, Griffonia simplicifolia - 5HTP, GRB6-GABA, B-Amino, and Ultra-Purified-FishOil, this will eventually lower the stress hormones and boost yout Prostaglandins E1 E3 and NO for healing, unless you have your hypthalamic-pituitary-testicular axis completely locked.
Tell us More
Hi Dr. Richards--
I run the support groups (2) for women who suffer PGAD---and have it myself--can you tell us more in simple terms what this comment means? I would love to know what you think is a cause, what you think women could try for relief--I cannot tell you how horrific it is to live with this--
Can you contact me at pgadsupport@gmail.com? I found this site by my Google Alerts that come into my gmail account --anything flagged with PGAD will be sent to me--if there is anything to know we want to hear it please--
www.psas-support.com
Best Regards-
Jeannie Allen
p.s.
Sorry--I didn't give my name--
Jeannie Allen, Founder of PSAS Support
Reply
Jeannie Allen,
I commend you for the works on the subject. It is always inspiring to help people.
Here is what I consider the problem:
When a woman turns certain age, in between 14 to 60(most frequently 28-34), the hypothalamic-pituitary-ovarian axis may start to produce less prolactin, in addition certain liver proteins may become low, thus an improper supression of abnormal prostaglandin E2, oxytocin, estrogen, DHT, and testosterone levels may be observed. Basically the persistent sexual arousal in women is a clitoral, vulva, uterine, and vaginal inflammation, this is a response to the increased prostaglandin E2, oxytocin, testosteron, DHT, and epinephrine levels.
The reasons to why is this happening are numerous:
The main cause for PSAS is physiological, basically every PSAS sufferer was "short" on proper inflammatory suppressive action by the nervous modulation, specifically Serotonin and GABA. Once a cycle of exitation and inflammations begins it additionally drains the needed resources for a proper modulation, so it(the cycle) has to be broken.
Generally speaking it can be done by doing the following things
1.A complete abstinence for a period of time
2.A balanced diet
3.A gradual rejuvenation of the neuro-endocrine function and nervous modulation on inflammatory and exitatory hormones.
This will most probably get things under control(where they should have been).
Wish you all the best!
Thank you for all this
Thank you for all this info--I did click the links to the web site for the things you suggested.
When you say a complete abstinence (which is the hardest thing for sufferers to do due to the pressure and distraction) between abstinence and using the suggested nutritional components, do you have any suggested ball park idea of a time frame that we would start to feel an improvement (as in an decrease in the tingling sensations)?
I know everyone is different but are we talking a month? Six months? A year? What about L-Arginine and Glutamine for the deepest inflammation along with balanced diet?
Do you see sugar in any form, sodas, chocolate, boxed food products as increasing inflammation at all? Or diet sodas with aspartame which is poisonous on it's own?
Thank you for being there--I have posted this link on the support groups --I have a feeling others will be coming here too--be prepared!
Best Regards-
Jeannie
Reply
Jaennie, It's my pleasure.
Yes, everyone's different, but speaking very roughly I would say that an improvement should be observed after a month.
There shouldn't be any need for additional L-arginine and Glutamine.
The refined sugar is absolutely harmful in every way. One can expect much problems for an already faulty endocrine system, and more inflammation as well. It's always a good idea to stay away from sugar.
One should stay away from diet sodas as well, or anything that may have suspicious ingredients. Just drink clean water.
I'm glad I've been helpful! My private practice consumes most of my time, but will make sure it won't take me more than several days to respond properly to everyone.
One other thing please
One other thing please Doctor--
Regarding what you feel is causing PGAD, could you tell me what research evidence you have to base this on?
Can you provide us with some references to published articles in
professional journals so that we might purchase and read them?
I think we should know this before we put out money for those items you listed.
Thank you--
Jeannie
Reply
Jeannie, of course. I plan to systematize the all references and publish them in a special article. Since they are more than 150 (the online sources) it will be time consuming, so I will create the ref. chapter in about 20 to 60 days.
Hormone-related PSAS
I have suffered with PSAS off and on for 20 years. I started at age 28 after coming off the birth control pill and it becomes worse at ovulation time and around my period. I would like to try one of the supplements that you recommended--mainly the Seronex--but I don't know if it is for women to use and if it might help me. I eat a fairly balanced diet but will definitely limit the sugar intake and the milk intake (unless it is organic). Please let me know what you think about the Seronex or other things I might try. Thank you.
Women and PSAS
I have suffered with PSAS off and on for about 20 years after coming of the BCP (I am 48 now). It is worst during ovulation and around my period (with vulvar swelling), but I still feel that the nerves in the genital area are sensitized most of the time--feeling prickly, tingly, achy, etc(even without swelling). I was wondering--do you recommend that women take all of the supplements that you suggest--especially the ones for men? One supplement stated that it will enhance sexual well-being. I want to suppress it more than enhance it. Also, should bloodwork be done before starting these supplements--ie testosterone, prolactin, prostaglandinE2 levels, etc. Do my symptoms fit into your theory for PSAS for women?
Another question--I find after sex, I don't have full resolution for a long time--sometimes 8 hours. The area stays swollen. I only have sex about once per week--not excessive--and I don't masturbate at all. Could this be related to hormone levels? I would appreciate any info you have. Thank you
Reply
Men are also suffering from altered neuroplasticity for additional excitatory and inflammation hormonal release to put their brains and internal organs in "heat" and it is actually what will bring them to sexual exhaustion later. The supplements will break the ill cycle by aiding the blown modulation on excitatory and inflammatory hormonal release, and in the same rejuvenating, healing, and altering the brain neuroplasticity and rewriting the reward circuits. So actually that means that the products will kill the sexual desire if it is caused by the wrong factors (example excessively binded prostaglandin E2) and later better the testicular functioning, thus creating stronger sexual desire that is not so severely based on inflammatory actions. This is true and for women, the dreaded self-supporting cycle of misregulation of certain hormonal releases and causes sexual excitation will be broken by the aided nervous modulation for normal functioning. A healthy sexual desire will then occur. There are now new products especially created for that exact purpose.
Are the new products what you
Are the new products what you suggested previously, or something new? Also would it help to get bloodwork, or would that matter? I am at a point in my cycle now where my hormone levels are rising (heading towards ovulation) and the genital area becomes somewhat swollen and actually hurts with some burning. Should I have bloodwork done when I feel the worst ( which will probably be in a day or so)? I would appreciate any feedback you can give me. Thank you.
Reply
They include most of the active ingredients of the previous products, but are bettered to provide even greater results.
A bloodwork in this case will be inconclusive. The burning and the slight pain is most probably caused by the excitatory and inflammatory hormone prostaglandin E2 present in the local tissues.
Would I need to take the
Would I need to take the Male-Multi GV since I am a woman?. And how long do these supplements need to be taken once they correct the problem? Would it come back if the supplements were stopped? Also, I am on a supplement called DIM that is an estrogen metabolizer. Would I need to come off of this? Thank you for all of your info.
Reply
You should replace Male-Multi-GV with Multi-AP to avoid some of the active ingredients in the first, that are designed to aid men.
Once the problem is corrected you should take them for at least 2 months to permanently change the negative neuroplasticity of excessive inflammatory and hormonal release that took place after the birth control pills discontinuation.
There should be no negative DIM interaction with the products. You may try and observe for yourself if DIM will prove to be of any particular assistance or not.