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Smoking and Sexual Activity

Sun, 01/10/2010 - 07:42 |  M.Richards

The major agent present in the tobacco is nicotine. It is a psychotropic agent, which mimics acetylcholine action in the cholinergic receptors, which in turn exert stimulatory effects on the mesolimbic dopaminergic function. Nicotine can increase DA outflow in the nucleus accumbens and corpus striatum. It will excite additional neuronal firing and will increase bursting activity of the DA neurons situated in the (SNc) and (VTA). Smoking also increases inflammatory hormone prostaglandin E2 production. A repeated usage will reinforce the effects thus causing an addiction.

Nicotine is also associated with a change of the sperm membranes and receptors, and a damage of the sperm DNA. By mimicing acetylcholine it will bind to a sperm cholinergic receptor that is responsible of the sperm's ability in fertilizing an egg.

Smoking will also result in an abnormal increase of the seminals' leukocyte counts by almost doubling it. An increased seminal leukocytic counts (white blood cells) is a clear sign of an ongoing inflammation within the reproductive tract, leading to poor quality and quantity of the semen. Smoking related oxidization stress explains the reduced sperm fertilizing capacity and increased oxidative damage to sperm DNA among male smokers.

A high levels of dopamine, serotonin and GABA nervous function will help you one overcome nicotine addiction.

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