Street drugs accompanied with excessive masturbation, ejaculation or sex may prove to be extremely destructive. In a direct or not so much manner, they usually alternate enzyme expressions, which results in numerous brain or nervous disorders. These disorders are usually a consequence of transferase gene expressions by tyrosine hydroxylase, dopamine hydroxylase and phenylethanolamine-N-methyl. Excessive masturbation, ejaculation or sex only adds prolactin and oxytocin to the picture. When one exhausts his acetylchloline or dopamine nervous system, though, he will suffer oxytocin deficiency and will experience difficulties with the excitement of the oxytocinergic nervous system in the hypothalamus.

Street drugs pollute the brain and nervous systems, alternate or destroy the gene expression of the nervous receptors or synapses. Neurodegeneration may occur, bringing its two widely known diseases – Parkinsons and Alzheimer. Mixing excessive sexual activity with street drugs is very dangerous. Over-ejaculation by itself is destructive enough – alternating the gene expression of dopamine receptors – D1 and D2, Serotonin C2 receptor, GABA A receptors and acetylcholine receptors.

Chronic use of street drugs will also directly damage testicular functioning and will interfere with the seminal production of the prostate.

The street or medication drugs also exert poisoning and damaging effect on the skins neuro-endocrine cells, and considering that the skin serves as a neuroendocrine organ for a production of neurotransmitters and hormonal production, the effect may prove to be devastating.

Liver is also heavily damaged by street drugs (nicotine, methamphetamine, cocaine), which leads to the destruction of liver’s detoxification system, thus leading to a reduction of ability to produce vital neurotransmitters and androgen hormones. One who uses street drugs is surely messing around with his dopamine, acetylcholine, serotonin and GABA nervous functioning.

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