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Excessive sexual activity discharges the brain's supply of acetylcholine, dopamine, serotonin, and GABA. This results in nervous, liver, kidney, cardiovascular, and endocrine disorders. A norepinephrine-epinephrine-sympathetic nervous fires occur, along with a high levels of prostaglandin E2, histamine, cortisol(too high or too low) and glutamate.

The neuro-endocrine system, if over-discharged, won't recharge by itself. Inflammation byproducts will damage or burn out many nervous cells, thus causing numerous ill symptoms. As an exhaustion of your pituitary-adrenal-testicular axis, the production of vital androgen hormones, such as: androstenedione, testosterone, DHEA, and DHT, plus the pituitary oxitocin will become too low to support your neuro-immune function, which is responsible for the supressing of the inflammatory hormone prostaglandin E2 release.

The inflammatory hormones - cortisol, prolactin, epinephrine, and norepinephrine, being excessive will disable your pituitary-testicular axis for a few days, weeks, or in the severe cases even months. This will make the refraction time extremely long, leading to a chronic sexual exhaustion and strange inflammations. Prostaglandin E2 will also be released from the tissues, leading to excitotoxicity in the brain cells, heart, lungs, liver, kidney, blood vessels, digestive system, prostate, gallbladder, pancreas, and testicles.

Since the semen is full of chemicals, one who over-ejaculates will lack zinc, calcium, citric acid, androgen hormones, spermine, potassium, fructose, phosphorylocholine, free amino acids(glycine, agmatine 5-HTP, and GABA), prostaglandinds E1 and E3, and numerous supporting enzymes.

During the sexual activity one may experience pro-inflammatory responses to the induced epinephrine-norepinephrine, but a lowered levels of DHEA, testosterone, androstenedione, DHT, and oxytocin, will be observed after several hours.

If one continue with these ill practices, the suppression of androgen hormones by the excessive cortisol and prolactin, along with the constriction the arteries in the brain, adrenal glands, lived, and testicles, will continue weakening your neuro-immune reactions to pro-inflammation, thus a prolonged time for a recovery will be observed.

Note that an excessive Prostaglandin E2 will also cause weak neuro-immunity

As a result of all of the above, sexual exhaustion produces multiple symptoms, which will become UFO for the doctors, failing to identify the root of the problems.

Sexual exhaustion symptoms include:

Memory loss - in the form of attention deficiency or/and losing memory, and mind concentration. This is caused by a deficiency of the neurotransmitters serotonin and acetylcholine, which are responsible for the memory protection.

Headaches or migraines - due to excessive release of the inflammatory hormone prostaglandin E-2, accompanied with dopamine-norepinephrine-epinephrine conversion in the brain, caused by the exhausted the acetylcholine, serotonin and GABA nervous system.

Tiredness and exhaustion - low levels of dopamine, and excessive prolactin that shuts down the testicular function, leading to failure in the parasympathetic nervous recharging system.

Weakness in the muscles - due to deficiency of testosterone, DHEA, and DHT.

Parkinson's symptoms(muscle tremors or twitching) - because of acetylcholine and dopamine deficiency.

Premature ejaculation - due to the low levels of serotonin and acetylcholine, accompanied with a damage of the prostate and urethral nerves.

Hair Loss - due to the excessive burning to DHT.

Low libido - due high levels of prolactin and deficiency of acetylcholine, dopamine, serotonin, and oxytocin

Vision Problems and Eye Floaters - due to disorders in the acetylcholine, and dopamine nervous circuits. A deficiency of proper serotonin-GABA nervous modulation in the retina, poor retinal blood circulation, and an arterial constriction.

Ear buzzing or ringing - due to a deficiency of normal nervous modulation.

Ejaculation pains or cramps in the pelvic cavity(low back, low abdomen, tail bone, penis, testicles, head) - due to a lack of prostaglandin E-1 in the local tissues, accompanied with unstable levels of acetylcholine, dopamine, serotonin, and GABA.

Depression and mood swings - due to unstable levels of all the vital neurotransmitters - acetylcholine, dopamine, serotonin, and GABA.

Watery ejaculation or even lack of ejaculation - due to weaked liver, adrenal, prostate, and testicular function.

Weak erection or youth impotence - due to locked hypothalamic-pituitary-adrenal-testicular axis for low levels of androgen hormones.

Prostatitis - due to excessive inflammatory Prostaglandin E2 production.

Penile shrinkage - due atrophy in the spongy tissues, lack of androgen hormones, and excessive stress hormone in the sympathetic alpha receptors.

Penile bending - due to excessive collagen release for a scar tissue, and nervous abrasion.

Irregular cardiovascular output - due to the weakened acetylcholine-serotonin and parasympathetic-vagus nervous function.

Sleeping disorders - due to lack of GABA and serotonin.

Frequent urination or urinary urgency - due to inflammatory response.

Excessive Sweating - due to a constant dopamine-norepinephrine-epinephrine conversion.

The symptoms can worsen with time.

The solution is to help your neuro-endocrine function and stabilize your serotonin and GABA nervous modulation on the Fight or Flight responses. You must also recharge your parasympathetic nervous system and boost your prostaglandin E-1 , E-3, oxytocin and Nitric Oxide production for healing.