Overactive sexual activities discharge the brain/nervous system’s supply of dopamine, serotonin, norepinephrine, GABA, and acetylcholine. This leads to nervous and endocrine disorders, affecting numerous organs and tissues. Excessive dopamine – norepinephrine – epinephrine conversions is also observed, both resulting and as a result of weakened serotonin – GABA nervous modulation on excitatory / inflammatory response for heightened inflammatory prostaglandin E2, cortisol, histamine, and glutamate.

The overly-discharched neuro-endocrine system then lacks much of its rejuvenating / restorative potential, resulting in a vicious cycle of inflammation and a negative neuroplasticity. Abundant inflammatory byproducts then lead to nervous cells toxicity, affecting numerous systems, organs, tissues, and one’s hypothalamic-pituitary-adrenal-testicular axis for either lowered androgens or PSAS if prolactin remains relatively low (frequently but not always as a result of harmful practices like edging).

The production of vital androgens, such as: DHEA, testosterone, androstenedione, and DHT, plus some additional neurotransmitters like oxytocin and Nitric Oxide becomes too low to support neuro-modulatory and immune functions responsible for prostaglandin E2, cortisol, histamine, glutamate regulation.

One’s hypothalamic – pituitary – adrenal – testicular axis will be disabled for a few days, weeks, or even months by inflammatory / excitatory cortisol, prolactin, norepinephrine, epinephrine. The refraction time will be lengthened leading to a chronic sexual exhaustion and a self supporting cycle of inflammation. As a result, excitotoxicity is observed in brain cells, heart, liver, kidneys, blood vessels, digestive system, prostate, pancrease, gallbladder, testicles, eyes, skin, bones, joints, and numerous soft tissues.

Ejaculation will spend much of the vital chemicals found in semen, as it is rich in: androgen hormones, free amino acids, zinc, calcium, magnesium, potassium, fructose, prostaglandins E1 E3, and numerous supporting enzymes.

Excessive pro-inflammatory responses to dopamine – norepinephrine – epinephrine conversions are frequently observed during sexual activities. Similar occurrences result in additionally lowered androgens and neurotransmitters for days or even weeks after.

The mentioned suppression of androgen hormones will only get worse if one continues engaging in over active sexual activities. Artery constriction in the brain, adrenal glands, liver, and testicles will spread to even larger blood vessels for a chronic fatigue and shortness of breath.

As a result of the above, Sexual Exhaustion will cause numerous symptoms depending on individual genotype and gene expressions.

Symptoms of Sexual Exhaustion include but are not limited to:

Fatigue, Tiredness, and Exhaustion – Predominantly related to lowered androgens (as a result of hypothalamic – pituitary – adrenal – testicular lock) and artery constriction, as well as improper acetylcholine levels predominantly responsible for proper muscle tissue functioning.

Depression and Mood Swings – related to improper serotonin and dopamine levels, as well as gradual anatomical alterations in the hypothalamus related to inflammatory processes.

Generalized Anxiety – Predominantly related to improper Serotonin – GABA nervous modulation on excitatory / inflammatory response.

Weak Erections – related to hypothalamic – pituitary – testicular axis lock for lowered androgens, as well as artery constriction and lack of sufficient elasticity prostaglandins E1 E3 and Nitric Oxide in penile tissues.

Memory Loss – caused by artery constriction and improper neurotransmitter levels in the brain (predominantly serotonin and acetylcholine) responsible for memory protection.

Muscle Weakness – caused by local tissue inflammation and testosterone, DHEA, and related androgen deficiency.

Muscle Tremors (Parkinson’s symptoms) – as a result of dopamine – acetylcholine deficiency.

Premature Ejaculation – due to low serotonin – GABA modulation on excitatory response, oversensitized tissues, and negative neuroplasticity.

Headaches and Migraines – due to artery constriction in the brain, excessive inflammatory prostaglandin E2, improper serotonin levels, and excessive dopamine – norepinephrine – epinephrine conversions.

Hair Loss  – as a result of excessive Testosterone – DHT conversions, skin inflammatory processes, and artery constriction.

Low Libido – due to hypothalamic – pituitary –adrenal – testicular axis lock for lowered androgens, as well as heightened prolactin, testicular shrinkage / artery constriction, and deficiency of dopamine and oxytocin.

Ear Buzzing and Ringing – due to shrinkage of the sound reception pathway through excessive epinephrine, shape alterations caused by deficiency of neurotransmitters and vital androgens, and numerous internal inflammatory processed to impact the tympanic membrane cavity and cochlea.

Ejaculatory and Low Back Pains – due to lack of sufficient prostaglandin E1 E3 for tissue elasticity, low androgens, artery narrowness, and local tissue inflammation.

Watery Ejaculation or Lack of Volume – due hypothalamic – pituitary –adrenal –testicular axis lock for low androgens and affected testicular and prostate functioning.

Urinary Urgency – as a result of constant excessive sympathetic responses as well as prostate – bladder pressure.

Excessive Sweating – as a result of constant dopamine – norepinephrine – epinephrine conversions and inflammatory processes.

Penile Injuries – as a result of low elasticity prostaglandin E1 E3 and Nitric Oxide, hypothalamic – pituitary – adrenal – testicular axis lock for lowered androgens (responsible for penile tissue health and integrity), and improper serotonin – GABA nervous modulation on inflammatory response for increased prostaglandin E2.

Penile Shrinkage – as a result of lowered androgens for spongy tissue atrophy, decreased prostaglandin E1 E3 and Nitric Oxide for lowered tissue elasticity, and a chronic artery constriction and inflammation.

Prostatitis – as a result of excessive inflammatory processes, low grade semen abrading the local tissues upon ejaculation, and excessive testosterone – DHT conversions.

Vision Problems and Eye Floaters – as a result of excessive glutamate in the nervous synapse, photoreceptors or retinal extracellular space, norepinephrine and epinephrine damage on retinal endothelial cells, low serotonin – GABA modulation of inflammatory response for inflamed eye balls and retina, and deficiency of dopamine, serotonin, GABA, glycine, agmatine and androgen hormones.

Insomnia and Sleeping Disorders – due to excessive sympathetic functioning, lack of serotonin, melatonin, and GABA.

Irregular Cardiovascular Output – due to lowered serotonin, dopamine, acetylcholine, and GABA levels, weakened nervous modulation on inflammatory / excitatory response, and artery constriction.