The inflammatory factors induced by excessive sexual activities result in hardening of the arteries, leading to hypertension, irregular cardio output (associated with weak serotonin – GABA nervous modulation on sympathetic action on the heart), and/or chest tension and pain.

The excess of norepinephrine-epinephrine result in different abnormalities in the sympathetic nerve for: post-sexual activity anxiety, sleeping disorders, and high blood pressure. Other symptoms such as: asthma, ear ringing, headaches, eye inflammation, and difficult breathing also usually occur.

The inflammation spreads individually through different gene expressions and may affect numerous internal tissues and organs.